p130 anticorps (N-Term)

N° du produit ABIN264369

Cet anticorps anti-p130 est un anticorps Souris Monoclonal détectant p130 dans WB. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour p130 anticorps (N-Term) (ABIN264369)

Antigène: p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p130 est non-conjugé

Application: Western Blotting (WB)

Clone: KAB40

Détail du produit anti-p130 anticorps

Épitope: N-Term

Specificité: This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130 kDa.

Attributs du produit: Synonyms: Retinoblastoma-like protein 2, RB2, 130 kDa retinoblastoma-associated protein, p130,Retinoblastoma-related protein 2, RBR-2, pRb2

Purification: Protein A/G chromatography.

Immunogène: GST fusion protein to the N terminus of p130.

Isotype: IgG1

Information d'application

Indications d'application: Suitable for Western Blots at 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch

Date de péremption: 12 months

Détails sur p130

Antigène: p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

Autre désignation: RBL2 / p130

Sujet: P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.Synonyms: 130 kDa retinoblastoma-associated protein, RB2, RBR-2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, p130, pRb2

ID gène: 5934

UniProt: Q08999

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases